Sr. Principal Scientist/Principal Scientist - Translational Autoimmunity

Company: Boehringer Ingelheim Pharmaceuticals
Location: Mentor
Posted on: September 13, 2020

Job Description:

Job Description - Sr. Principal Scientist/Principal Scientist - Translational Autoimmunity (204667)

Boehringer Ingelheim is an equal opportunity global employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment which benefits our employees, patients and communities.

Sr. Principal Scientist/Principal Scientist - Translational Autoimmunity - 204667

Candidate will be hired at level commensurate with experience and education

Description:

The  Sr. Principal Scientist or Principal Scientist  is primarily responsible for performing and managing scientific and technical activities, which may also include responsibility for the management of scientific staff. Proficient or develop expertise in scleroderma and expand knowledge on other immunology and respiratory research areas by keeping abreast of relevant literature. Candidate must have strong analytical and problem-solving skills with proven track record of high research accountability and productivity both independently with minimal supervision and within a team setting in a matrix environment.

Lead a group of scientists to experimentally develop differentiated disease positioning concepts for New therapeutic concepts in Scleroderma, to support I&R Discovery Research portfolio development. Work with Biomarker and Translational systems groups to collaboratively establish and implement data packages that will help teams deliver on early concepts for patient stratification. Establish and maintain external collaborations to utilize patient samples for developing disease linkages and to strengthen value proposition of drug concepts.Manage and prioritize multiple projects within the laboratory and interface with other immunology and respiratory labs.As appropriate, serve as the biology Research Project Leader on portfolio projects.Define, implement and communicate tactics for achieving overall R&D project goals.Mentor junior staff for effective planning and conduct of laboratory experiments and thorough evaluation and interpretation of data.Responsible for the management and development of scientific staff.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities:

Develop and implement experimental ideas for delivering highly differentiated disease positioning concepts for targets in portfolio. Keep abreast of current literature and drive novel science by implementing assays to address contribution of vasculopathy, inflammation and aberrant tissue remodeling relevant to scleroderma.

Ability to lead a group of scientists by directing and overseeing the design, execution and interpretation of studies.

As appropriate, serve as project Leader on portfolio projects.Responsible for working in collaboration with the Medicinal Chemistry or Biotherapeutics project leaders to shape and drive project strategy and advance the project up to start of clinical development.

Skilled in human cellular assay systems linked to fibrosis to establish strong NTC to disease linkage concepts using state of the art human disease ex vivo/in vitro models.

Collaborate with in vivo group to enable back translation of human disease-relevant mechanisms to in vivo models

Responsible for leading external collaborations and for establishing an external network to recruit and develop entry level Ph.D. and laboratory staff within the scleroderma disease positioning group.

Influence overall portfolio through engagement of departmental scientific reviews and providing strategic recommendations that will have impact on project direction and progression.

Develop scientific staff and mentor them in their experiments and for creating growth opportunities

Ensure compliance with all required training, safety, regulatory, HR, laboratory notebook, and intellectual property activities and corporate policies.

Sr. Principal Scientist Requirements:

Doctoral degree with at least 7 years drug discovery experience in pharmaceutical industry or biotech, or equivalent.

A proven track record of high research productivity in immunology and fibrotic diseases. Deep understanding of mechanisms and pathways in skin and fibrotic diseases and current treatment modalities.

Ability to mentor Ph.D. scientists and lead a group of bench scientist(s) to deliver high quality data to contribute to overall program goals. Ability to proactive identification of critical issues and communicate effectively both orally and in writing in an inter-disciplinary environment.

The successful candidate will be an ambitious self-starter, be motivated to apply his/her skills to impact project needs and drive key innovative scientific concepts, and enjoy working in a fast-paced dynamic team environment and proven ability to focus and deliver high quality data that support timely decisions for projects.

Principal Scientist Requirements:

Doctoral degree with at least 5 years drug discovery experience in pharmaceutical industry or biotech, or equivalent.

A proven track record of high research productivity in immunology and fibrotic diseases. Deep understanding of mechanisms and pathways in skin and fibrotic diseases and current treatment modalities.

Ability to mentor Ph.D. scientists and lead a group of bench scientist(s) to deliver high quality data to contribute to overall program goals. Ability to proactive identification of critical issues and communicate effectively both orally and in writing in an inter-disciplinary environment.

The successful candidate will be an ambitious self-starter, be motivated to apply his/her skills to impact project needs and drive key innovative scientific concepts, and enjoy working in a fast-paced dynamic team environment and proven ability to focus and deliver high quality data that support timely decisions for projects.

Eligibility Requirements: Must be legally authorized to work in the United States without restriction.

Must be willing to take a drug test and post-offer physical (if required)

Must be 18 years of age or older

Who We Are:

At Boehringer Ingelheim we create value through innovation with one clear goal: to improve the lives of patients. We develop breakthrough therapies and innovative healthcare solutions in areas of unmet medical need for both humans and animals. As a family owned company we focus on long term performance. We are powered by 50.000 employees globally who nurture a diverse, collaborative and inclusive culture. Learning and development for all employees is key because your growth is our growth.

Boehringer Ingelheim, including Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim USA, Boehringer Ingelheim Animal Health USA Inc., Boehringer Ingelheim Animal Health Puerto Rico LLC and Boehringer Ingelheim Fremont, Inc. is an equal opportunity and affirmative action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; citizenship status, marital, domestic partnership or civil union status; gender, gender identity or expression; affectional or sexual orientation; pregnancy, childbirth or related medical condition; physical or psychiatric disability; veteran or military status; domestic violence victim status; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by applicable federal, state or local law.

Keywords: Boehringer Ingelheim Pharmaceuticals, Mentor , Sr. Principal Scientist/Principal Scientist - Translational Autoimmunity, Other , Mentor, Ohio